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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMF1 All Species: 27.88
Human Site: S933 Identified Species: 38.33
UniProt: P82094 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P82094 NP_009045.2 1093 122842 S933 V S S T P T M S R S S S I S G
Chimpanzee Pan troglodytes XP_526227 1093 122795 S933 V S S T P T M S R S S S I S G
Rhesus Macaque Macaca mulatta XP_001088711 1092 122828 S932 V S S T P T M S R S S S I S G
Dog Lupus familis XP_533766 1089 122761 M929 S V S S T P T M S R S S S I S
Cat Felis silvestris
Mouse Mus musculus B9EKI3 1091 121796 S931 V C S T P T M S R S S S I S G
Rat Rattus norvegicus NP_446123 1093 121882 S933 V S S T P T M S R S S S L S G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510334 1106 124384 S946 V S S T P T L S R S S S I S G
Chicken Gallus gallus O42184 1433 161009 M1204 L N N Q L L E M K K R E S T L
Frog Xenopus laevis Q5PQ23 649 75475 Q499 S L L E K L H Q Q T T E N T C
Zebra Danio Brachydanio rerio NP_001003522 1136 126986 R976 S S T P S L S R S S S V S G A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572360 933 103794 D782 E A L G G M I D W Q A D D L D
Honey Bee Apis mellifera XP_394037 1326 150590 S1048 E A R S E E L S E S V S M A T
Nematode Worm Caenorhab. elegans P02566 1966 225108 E1567 E A A L E A E E S K V L R A Q
Sea Urchin Strong. purpuratus XP_785821 1176 131318 S1017 S G S P S P S S R A S T P V H
Poplar Tree Populus trichocarpa XP_002303293 975 109171 E825 S S L G S I E E S Y F L Q A S
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q0WVL7 956 108335 S806 S L P R K L S S A S S L G S M
Baker's Yeast Sacchar. cerevisiae P47166 707 81153 A557 I D D I P E E A A A L Q A I R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 98.5 93.1 N.A. 87.2 86.7 N.A. 81.2 21.7 22.6 59.7 N.A. 26.1 23.9 21 37.7
Protein Similarity: 100 99.4 99.1 96.1 N.A. 92.5 92 N.A. 88.3 39.9 37.3 74.6 N.A. 45.8 44.9 36.6 56.8
P-Site Identity: 100 100 100 20 N.A. 93.3 93.3 N.A. 93.3 0 0 20 N.A. 0 20 0 26.6
P-Site Similarity: 100 100 100 26.6 N.A. 93.3 100 N.A. 100 33.3 26.6 26.6 N.A. 20 53.3 20 40
Percent
Protein Identity: 25.8 N.A. N.A. 27.1 21.1 N.A.
Protein Similarity: 47.2 N.A. N.A. 45.4 39.4 N.A.
P-Site Identity: 6.6 N.A. N.A. 26.6 6.6 N.A.
P-Site Similarity: 13.3 N.A. N.A. 26.6 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 18 6 0 0 6 0 6 12 12 6 0 6 18 6 % A
% Cys: 0 6 0 0 0 0 0 0 0 0 0 0 0 0 6 % C
% Asp: 0 6 6 0 0 0 0 6 0 0 0 6 6 0 6 % D
% Glu: 18 0 0 6 12 12 24 12 6 0 0 12 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 6 0 0 0 0 % F
% Gly: 0 6 0 12 6 0 0 0 0 0 0 0 6 6 36 % G
% His: 0 0 0 0 0 0 6 0 0 0 0 0 0 0 6 % H
% Ile: 6 0 0 6 0 6 6 0 0 0 0 0 30 12 0 % I
% Lys: 0 0 0 0 12 0 0 0 6 12 0 0 0 0 0 % K
% Leu: 6 12 18 6 6 24 12 0 0 0 6 18 6 6 6 % L
% Met: 0 0 0 0 0 6 30 12 0 0 0 0 6 0 6 % M
% Asn: 0 6 6 0 0 0 0 0 0 0 0 0 6 0 0 % N
% Pro: 0 0 6 12 42 12 0 0 0 0 0 0 6 0 0 % P
% Gln: 0 0 0 6 0 0 0 6 6 6 0 6 6 0 6 % Q
% Arg: 0 0 6 6 0 0 0 6 42 6 6 0 6 0 6 % R
% Ser: 36 42 48 12 18 0 18 53 24 53 59 48 18 42 12 % S
% Thr: 0 0 6 36 6 36 6 0 0 6 6 6 0 12 6 % T
% Val: 36 6 0 0 0 0 0 0 0 0 12 6 0 6 0 % V
% Trp: 0 0 0 0 0 0 0 0 6 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 6 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _